Efficacy and safety of transepithelial collagen crosslinking for progressive keratoconus

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Efficacy and safety of transepithelial collagen cross linking for progressive keratoconus

OBJECTIVE To evaluate the efficacy and safety of transepithelial (TE) collagen cross-linking (CXL) in patients with progressive keratoconus (KC). METHODS This Quasi Experimental Study was conducted at PNS Shifa Naval Hospital, Karachi from June 2015 to June 2016. Sixty eyes of 32 patients who underwent TE CXL for progressive KC from June 2015 to June 2016 were analysed to ascertain efficacy a...

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Transepithelial corneal collagen crosslinking for keratoconus: six-month results.

PURPOSE To evaluate the safety and efficacy of corneal collagen crosslinking (CXL) using a transepithelial technique to treat keratoconus. SETTING Cornea and refractive surgery subspecialty practice. DESIGN Prospective clinical trial. METHODS Transepithelial CXL was performed in eyes with keratoconus using proparacaine with benzalkonium chloride (BAK) 0.01% to facilitate riboflavin absorp...

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Efficacy and safety of transepithelial corneal collagen crosslinking surgery versus standard corneal collagen crosslinking surgery for keratoconus: a meta-analysis of randomized controlled trials

BACKGROUND The aim of this study was to evaluate the efficacy and safety of transepithelial corneal collagen crosslinking (transepithelial CXL) versus standard corneal collagen crosslinking (epithelium-off CXL) on keratoconus. METHODS Eligible studies were identified by systematically searching PubMed, the Cochrane Library and Embase. Topographic parameters, corrected distant visual acuity (C...

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Efficacy of transepithelial corneal collagen crosslinking for keratoconus: 12-month follow-up

PURPOSE To evaluate the efficacy of transepithelial corneal collagen crosslinking (TE-CXL) in patients with progressive keratoconus. PATIENTS AND METHODS This is a prospective interventional consecutive study carried out on 30 eyes of 18 patients with progressive keratoconus who underwent TE-CLX using both ParaCel™ (riboflavin 0.25%, hydroxy propyl methyl cellulose, NaCl, ethylenediaminetetra...

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Collagen Crosslinking for Keratoconus

In this issue of JOVR, Derakhshan and co-authors 1 describe the results of crosslinking for patients with early keratoconus. Collagen crosslinking is a recently described technique of corneal tissue strengthening using riboflavin as a photosensitizer and ultraviolet A (UVA) radiation to promote the formation of intra-and interfibrillar covalent bonds by photosensitized oxidation. 2 To date, it ...

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ژورنال

عنوان ژورنال: Pakistan Journal of Medical Sciences

سال: 2016

ISSN: 1681-715X

DOI: 10.12669/pjms.325.10922